Biotin and derivatives
Medchemexpress LLC PD-L1 Human Biotin 20ug
Recombinant, biotinylated human PD-L1 produced in HEK293 cells and supplied as a lyophilized 20 μg vial for research use. The protein includes C-terminal human Fc and Avi tags, is characterized for purity and molecular mass, and exhibits specific binding activity suitable for PD-1/PD-L1 interaction and immunoassay applications.
- Expressed in HEK293 mammalian cells.
- Contains C-terminal human Fc and Avi tags.
- Site-specific biotinylation via Avi tag.
- Purity greater than 95% by reducing SDS-PAGE.
- Lyophilized from 20 mM PB, 150 mM NaCl, pH 7.4.
- Predicted molecular mass 54.2 kDa; apparent 70-95 kDa by SDS-PAGE.
- Demonstrated binding activity with ED50 of 15.30 ng/mL.
- Store frozen and aliquot after reconstitution for long-term stability.
Medchemexpress LLC Biotin-PEG3-acid 100mg | 252881-76-8 | 100 MG
Biotin-PEG3-acid is a biotin-labeled polyethylene glycol (PEG3) linker containing a terminal carboxylic acid. It is supplied as a purified research-grade small molecule for use in PROTAC synthesis and biotinylation applications.
- Biotin-labeled PEG3 linker with terminal carboxylic acid.
- Designed for PROTAC synthesis and biotinylation workflows.
- High purity, 98.0%.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store sealed at 4°C; in solution store at -80°C for long-term stability.
- Available in 100 MG and larger pack sizes for research use.
Medchemexpress LLC Mal-PEG12-NHS ester | 2669737-09-9 | MFCD31811553 | 97.0% | C35H58N2O18 | 10MG
Mal-PEG12-NHS ester is a heterobifunctional PEG12 linker bearing a maleimide and an N-hydroxysuccinimide (NHS) ester. It enables efficient, site-selective conjugation of sulfhydryl-containing molecules to primary amines through a hydrophilic PEG12 spacer, and is commonly used in PROTAC synthesis and general bioconjugation workflows. Molecular weight ≈794.84 g·mol⁻¹; CAS 2669737-09-9; typical purity ≈97%.
- Heterobifunctional maleimide-NHS chemistry for thiol-to-amine conjugation.
- PEG12 spacer increases solubility and reduces steric hindrance.
- Suitable for PROTAC linker synthesis and general bioconjugation.
- High purity (~97%) for reliable analytical and preparative use.
- Available in small-scale quantities for research applications.
Medchemexpress LLC Biotin-PEG3-bromide | 1041766-91-9 | 95.0% | 482.43 g/mol | C18H32BrN3O5S | 50 MG
Biotin-PEG3-bromide is a biotinylated short polyethylene glycol (PEG3) linker terminated with an alkyl bromide. The bromide serves as a reactive leaving group for nucleophilic substitution or cross-coupling reactions, while the biotin enables affinity capture via streptavidin. The PEG3 spacer improves solubility and reduces steric hindrance in bioconjugation and pull-down assays.
- Reactive alkyl bromide for nucleophilic substitution and cross-coupling
- Biotin moiety enables affinity capture with streptavidin
- PEG3 spacer enhances solubility and reduces steric hindrance
- High purity (95.0%) suitable for analytical and preparative use
- Available in small quantities for research use (50 MG)
Medchemexpress LLC DBCO-NHS ester 2 1g | 1384870-47-6 | 1 G
DBCO-NHS ester 2 is a dibenzoazacyclooctyne (DBCO)-containing N-hydroxysuccinimide (NHS) ester reagent for strain-promoted alkyne-azide cycloaddition (SPAAC). It is used to install a DBCO handle on amine-containing molecules for copper-free click conjugation to azide-functionalized partners and as a cleavable linker in bioconjugation workflows.
- Amine-reactive NHS ester for efficient coupling to primary amines.
- DBCO group enables strain-promoted copper-free click chemistry with azides.
- Suitable for bioconjugation and linker formation in antibody-drug conjugates.
- High reported purity for reproducible conjugation performance.
- Supplied as a 1 g quantity for small-scale synthesis and labeling.
![Medchemexpress LLC Carbonic acid, 1-[4-[(16-azido-PEG3)oxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-pyrrolidinyl ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 g/mol | C26H36N6O13 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000280727.png-250.jpg)
Medchemexpress LLC Carbonic acid, 1-[4-[(16-azido-PEG3)oxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-pyrrolidinyl ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 g/mol | C26H36N6O13 | 50 MG
PC Azido-PEG3-NHS carbonate ester is a photocleavable azido-PEG3 NHS carbonate linker for labeling primary amines on proteins, amine-modified oligonucleotides, and other amine-containing molecules. It combines an NHS carbonate reactive group with an azide handle and a photocleavable moiety to enable covalent labeling and light-triggered release. Supplied as a colorless to light-yellow oil for research use; follow manufacturer storage recommendations.
Medchemexpress LLC L-biotin | 21788-37-4 | 99.7% | 244.31 g/mol | C10H16N2O3S | 10 MG
L-biotin is the unnatural enantiomer of biotin provided as a research-grade chemical standard for stereochemical studies and analytical applications. It is supplied with a certificate of analysis and a safety data sheet to support safe handling and quality verification.
- high reported purity suitable for analytical use
- available in small milligram pack sizes for research
- comes with COA and SDS documentation
- chemical formula C10H16N2O3S and molecular weight 244.31 g/mol
- intended for research use only; not for human use